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Substance Information
Substance information
Infocards are automatically generated based on industry data. What is an infocard?
Sulindac
Substance identity The ‘Substance identity’ section links substance identification information from all ECHA databases. The substance identifiers displayed in the InfoCard are the substance name, substance identifiers (EC and CAS number) and/or the molecular formula.
Substance identifiers may have been claimed confidential, or may not have been provided, and therefore not displayed.
EC (European Community) number
The EC Number is the numerical identifier for substances in the EC Inventory. The EC Inventory is a combination of three independent European lists of substances from the previous EU chemicals regulatory frameworks (EINECS, ELINCS and the NLP-list). More information about the EC Inventory can be found here.
If the substance was not covered by the EC Inventory, ECHA attributes a list number in the same format, starting with the numbers 6, 7, 8 or 9.
The EC or list number is the primary substance identifier used by ECHA.
CAS (Chemical Abstract Service) registry number
The CAS number is the substance numerical identifier assigned by the Chemical Abstract Service, a division of the American Chemical Society, to substances registered in the CAS registry database. A substance identified primarily by an EC or list number may be linked with more than one CAS number, or with CAS numbers that have become obsolete. In these cases, the preferred CAS number is displayed first and obsolete CAS numbers are displayed in brackets. More information about CAS and the CAS registry can be found here.
Molecular formula
The molecular formula identifies each type of element by its chemical symbol and identifies the number of atoms of each element found in one discrete molecule of the substance. This information is only displayed if the substance is well–defined, if such information is available in ECHA’s database and is it not claimed confidential.
Molecular structure
The molecular structure is based on InChI annotations stored in the ECHA database. The image is a computer–generated visualisation of the InChI character string, which is broadly used as an identifier of chemical structures. This information is only displayed if the substance is well-defined, if such information is available in ECHA’s database and is it not claimed confidential.
More help available here.
EC / List no.: 253-819-2
CAS no.: 38194-50-2
Mol. formula: C20H17FO3S
Hazard classification and labelling The ‘Hazard classification and labelling’ section shows the hazards of a substance through a standardised system of statements and pictograms, as has been established under the CLP (Classification Labelling and Packaging) Regulation. The CLP Regulation makes sure that the hazards presented by chemicals are clearly communicated to workers and consumers in the European Union. The CLP Regulation uses the UN Global Harmonised System (GHS) and European Union Specific Hazard Statements (EUH).
This section searches three sources for information (harmonised classification and labelling (CLH), REACH registrations and CLP notifications). The source of the information is mentioned in the introductory sentence of the hazard statements. When information is available in all sources, the first two are displayed as a priority.
Please note:
The purpose of the information provided under this section is to highlight the substance hazardousness in a readable format. It does not represent a new labelling, classification or hazard statement, neither reflect other factors that affect the susceptibility of the effects described, such as duration of exposure or substance concentration (e.g. in case of consumer and professional uses). Other relevant information includes the following:
- Substances may have impurities and additives that lead to different classifications. If at least one company has indicated that the substance classification is affected by impurities or additives, this will be indicated by an informative sentence. However, substance notifications in the InfoCard are aggregated independently of the impurities and additives.
- Hazard statements were adapted to improve readability and may not correspond textually to the hazard statements codes description in the European Union Specific Hazard Statements (EUH) or the UN Global Harmonised System (GHS).
To see the full list of notified classifications and to get more information on impurities and additives relevant to classification please consult the C&L Inventory.
More information about Classification and Labelling is available in the Regulations section of ECHA website.
More help available here.
Harmonised classification and labelling (CLH)
Harmonised classification and labelling is a legally binding classification and labelling for a substance, agreed at European Community level. Harmonisation is based on the substance’s physical, toxicological and eco-toxicological hazard assessment.
The ‘Hazard classification’ and labelling section uses the signal word, pictogram(s) and hazard statements of the substance under the harmonised classification and labelling (CLH) as its primary source of information.
If the substance is covered by more than one CLH entry (e.g. disodium tetraborate EC no. 215–540–4, is covered by three harmonisations: 005–011–00–4; 005–011–01–1 and 005–011–02–9), CLH information cannot be displayed in the InfoCard as the difference between the CLH classifications requires manual interpretation or verification. If a substance is classified under multiple CLH entries, a link to the C&L Inventory is provided to allow users to view CLH information associated with the substance, instead of having the information automatically generated in the InfoCard.
It is possible that a harmonisation is introduced through an amendment to the CLP Regulation. In that case, the ATP (Adaptation to Technical Progress) number is displayed.
More info on CLH can be found here.
Classification and labelling under REACH
If available, additional information on classification and labelling (C&L) is derived from REACH registration dossiers submitted by industry. This information has not been reviewed or verified by ECHA, and may change without prior notice. REACH registration dossiers have greater data requirements (support studies) than notifications under CLP.
Notifications under the Classification Labelling and Packaging (CLP) Regulation
If no EU harmonised classification and labelling exists and the substance was not registered under REACH, information derived from classification and labelling (C&L) notifications to ECHA under CLP Regulation is displayed under this section. These notifications can be provided by manufacturers, importers and downstream users. ECHA maintains the C&L Inventory, but does not review or verify the accuracy of the information.
For readability purposes, only the pictograms, signal words and hazard statements referred in more than 5% of the notifications under CLP are displayed.
Danger! According to the classification provided by companies to ECHA in CLP notifications this substance is toxic if swallowed, may damage fertility or the unborn child, causes serious eye irritation, may cause damage to organs through prolonged or repeated exposure, is suspected of damaging fertility or the unborn child, may cause an allergic skin reaction and may cause allergy or asthma symptoms or breathing difficulties if inhaled.
Properties of concern The ‘Properties of concern’ section shows ECHA-assigned graphical indicators for certain substance properties that are regarded as critical for human health and/or the environment based on the information provided to the Agency. The following properties have been highlighted as critical:
C – Carcinogenic (i.e. classified in carcinogenicity categories 1A or 1B). More information about carcinogenicity here.
M – Mutagenic (i.e. classified in mutagenicity categories 1A or 1B). More information about mutagenicity here.
R – Toxic to reproduction (i.e. classified in reproductive toxicity categories 1A or 1B). More information about reproductive toxicity here.
Ss – Skin sensitiser (i.e. classified in skin sensitisation categories 1, 1A or 1B). More information about skin sensitiser here.
Sr – Respiratory sensitiser (i.e. classified in respiratory sensitisation categories 1, 1A or 1B). More information about respiratory sensitiser here.
PBT – Persistent, bioaccumulative and toxic (PBT). More information about persistent, bioaccumulative and toxic substances here.
The substance properties displayed in this section (with the exception of PBT properties) are derived from harmonised classification and labelling (CLH) and/or REACH registered dossier information. In case the substance classification is not harmonised and the substance is not registered the properties are derived from classifications provided in CLP notifications. PBT properties are derived from REACH registered dossiers.
Critical property indentification: Where less than 90% of the notifiers provide the same classification to derive the critical property, the border of this critical property icon is displayed as dashed.
Impurities or additives: When a specific critical property is associated with compositions with impurities and/or additives, the respective critical property icon has a * associated.
More help available here.
- R
- Ss
- Sr
The InfoCard summarises the non-confidential data of a substance held in the databases of the European Chemicals Agency (ECHA). InfoCards are generated automatically based on the data available at the time of generation.
The quality and correctness of the information submitted to ECHA remains the responsibility of the data submitter. The type of uses and classifications may vary between different submissions to ECHA and for a full understanding it is recommended to consult the source data. Information on applicable regulatory frameworks is also automatically generated and may not be complete or up to date. It is the responsibility of the substance manufacturers and importers to consult official publications, e.g. the electronic edition of the Official Journal of the European Union.
InfoCards are updated when new information is available. The date of the last update corresponds to the publication date of the InfoCard and not necessarily to the date in which the update occurred in the source data.
More help available here.
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