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Sulprostone From Wikipedia, the free encyclopedia Jump to navigation Jump to search Sulprostone Clinical data AHFS/Drugs.com International Drug Names ATC code G02AD05 ( WHO ) Identifiers IUPAC name (Z)-7-[(1R,3R)-3-hydroxy-2-[(E,3R)-3-hydroxy-4-phenoxybut-1-enyl]-5-oxocyclopentyl]-N-methylsulfonylhept-5-enamide CAS Number 60325-46-4   N PubChem CID 5312153 ChemSpider 4471583   N UNII 501Q5EQ1GM KEGG D02725   Y ChEMBL ChEMBL284178   N ECHA InfoCard 100.056.503 Chemical and physical data Formula C 23 H 31 N O 7 S Molar mass 465.56 g/mol 3D model (JSmol) Interactive image SMILES CS(=O)(=O)NC(=O)CCC/C=CC[C@@H]1[C@H]([C@@H](CC1=O)O)/C=C/[C@H](COc2ccccc2)O InChI InChI=1S/C23H31NO7S/c1-32(29,30)24-23(28)12-8-3-2-7-11-19-20(22(27)15-21(19)26)14-13-17(25)16-31-18-9-5-4-6-10-18/h2,4-7,9-10,13-14,17,19-20,22,25,27H,3,8,11-12,15-16H2,1H3,(H,24,28)/b7-2-,14-13+/t17-,19-,20-,22-/m1/s1   N Key:UQZVCDCIMBLVNR-TWYODKAFSA-N   N .mw-parser-output .noboldfont-

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Lubiprostone From Wikipedia, the free encyclopedia Jump to navigation Jump to search This article needs additional citations for verification . Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed. ( April 2014 ) (Learn how and when to remove this template message) Lubiprostone Clinical data Trade names Amitiza Synonyms Amitiza RU-0211 SPI-0211 AHFS/Drugs.com Monograph MedlinePlus a607034 License data US   FDA: Lubiprostone Pregnancy category US : C (Risk not ruled out) Routes of administration Oral ATC code A06AX03 ( WHO ) Legal status Legal status US : ℞-only Pharmacokinetic data Bioavailability Negligible Protein binding 94% Metabolism Extensive, CYP not involved Elimination half-life Unknown (lubiprostone) 0.9–1.4 hours (main metabolite) Excretion Renal (60%) and fecal (30%) Identifiers IUPAC name 7-[(1 R ,3 R ,6 R ,7 R )-3-(1,1-Difluoropentyl)-3-hydroxy-8-oxo-2-