抗磷脂综合征

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抗磷脂综合征
同义词
Hughes syndrome[1]

Thrombotic microangiopathy - very high mag.jpg

Micrograph showing an advanced thrombotic microangiopathy英语thrombotic microangiopathy, as may be seen in ALPA syndrome. Kidney biopsy英语Kidney biopsy. PAS stain.
分类和外部资源
醫學專科
风湿病学

ICD-10

D68.6 (ILDS英语ILDS D68.810)

ICD-9-CM

ICD9 289.81
OMIM
107320
DiseasesDB
775
eMedicine
med/2923
Patient UK
抗磷脂综合征
MeSH
D016736

[编辑此条目的维基数据]

抗磷脂综合征英语:Antiphospholipid syndromeAPSAPLS)是由于人体免疫系统对细胞膜成分磷脂发生异常自身免疫,产生抗体所引起的一组征候群。主要症状有动脉或者静脉血管栓塞、血小板减少以及与怀孕相关的胎死腹中、早产和自发性流产等,同时伴有抗心磷脂或者狼疮抗凝物实验持续阳性。


患者体内免疫功能失调会产生多种自身抗体。这些抗体引起血小板减少,同时破坏血管内皮细胞的完整性,导致血栓形成。怀孕妇女由于胎盘动静脉发生血栓,从而使得胎盘供血受阻,导致流产。



参考文献


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  • Triona Holden. Positive Options for Antiphospholipid Syndrome (APS): Self-Help and Treatment. Hunter House (CA). 2003. ISBN 0-89793-409-1. 


  • Kay Thackray. Sticky Blood Explained. Braiswick. 2003. ISBN 1-898030-77-4.  A personal account of dealing with the condition.


  • Graham R V Hughes. Understanding Hughes Syndrome: Case Studies for Patients. Springer. 2009. ISBN 1-84800-375-7.  50 case studies to help you work out whether you have it.


  • 原发性抗磷脂综合征诊疗指南[永久失效連結]



外部連接


  • APS Foundation of America, Inc.

  • Hughes Syndrome Foundation


  • Hughes Syndrome: simple to treat but all too often ignored - Interview with Hughes; The Telegraph, 2 February 2009; Accessed 18 November 2016

Template:Diseases of megakaryocytes



  1. ^ Hughes, Graham; Khamashta, Munther A. Hughes Syndrome: Highways and Byways. Springer Science & Business Media. ISBN 9781447151616 (英语). 

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