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Antrafenine








Antrafenine


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Antrafenine
Antrafenine.svg
Clinical data
Routes of
administration		Oral
ATC code
  • none
Legal status
Legal status

  • In general: ℞ (Prescription only)


Pharmacokinetic data
MetabolismHepatic
ExcretionRenal
Identifiers
CAS Number

  • 55300-30-6 ☑Y

PubChem CID
  • 68723
DrugBank

  • DB01419 ☑Y
ChemSpider

  • 61973 ☑Y
UNII
  • 21FS93Y6OE
ChEMBL

  • ChEMBL345524 ☑Y
Chemical and physical data
Formula
C30H26F6N4O2
Molar mass588.543 g/mol
3D model (JSmol)
  • Interactive image

.mw-parser-output .noboldfont-weight:normal
  (verify)

Antrafenine (Stakane) is a phenylpiperazine derivative drug invented in 1979.[1] It acts as an analgesic and anti-inflammatory drug with similar efficacy to naproxen,[2] but is not widely used as it has largely been replaced by newer drugs.



See also[edit]


  • Phenylpiperazine

  • Trifluoromethylphenylpiperazine


References[edit]




  1. ^ Manoury PM, Dumas AP, Najer H, Branceni D, Prouteau M, Lefevre-Borg FM. Synthesis and analgesic activities of some (4-substituted phenyl-1-piperazinyl)alkyl 2-aminobenzoates and 2-aminonicotinates. Journal of Medicinal Chemistry. 1979 May;22(5):554-9.


  2. ^ Leatham PA, Bird HA, Wright V, Seymour D, Gordon A. A double blind study of antrafenine, naproxen and placebo in osteoarthrosis. European Journal of Rheumatology and Inflammation. 1983;6(2):209-11.











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